provides nutritional building blocks to promote natural joint health, stability, and flexibility, plus a healthier skin and coat. As a dietary ingredient BiovaPlex® helps:*


• Improve range of motion; i.e. mobility, flexibility, and function

• Promote a natural anti-inflammatory response**

• Provide antioxidants that reduce free radicals for healthy joints

• Provide collagen and other beneficial nutrients for a lustrous, healthy coat

• Increase energy levels

What is BiovaPlex®? 

BiovaPlex® is a nutraceutical ingredient targeting animal health applications. Developed via Biova’s patented Hydro5 process which retains the natural ratios of joint nutrients found in egg membrane, BiovaPlex® features these key elements:

• Collagen—fibrous protein critical to cartilage strength and elasticity 

• Elastin—a protein critical to skin, cardiovascular, cartilage, and spinal column health; Elastin gives tissue the elastic tension and ability to resume its shape after stretching 

• Desmosine and Isodesmosine—two little known amino acids responsible for elastin’s elastic or “rubbery” properties

• Glycosaminoglycans (GAGs) including: Glucosamine and Chondroitin—vital polysaccharides which serve as structural components of connective tissue, interstitial fluids, and skeletal structures 


 Is BiovaPlex supported by research?  YES!

InVitro studies demonstrated statistically significant inhibition of Reactive Oxygen Species (ROS) formation, Lipoxygenase inhibition. Strong migratory behavior in PMN cells was observed along with response to the IL-8 and LTB4 mediators, with a particular strong and clear inhibition of LTB4-mediated migration exhibited. Apoptotic and necrotic cell death were also reduced under conditions of oxidative stress.**

Clinical Efficacy research in fifty-seven (57) canines with limited joint mobility demonstrated positive changes within 7 days; all subjects exhibited increased activity and mobility by the conclusion of the 28-day study.

Human Joint Health research with forty-two (42) subjects symptoms reduced by 8.25% after 7 days and 16.42% after 14 days. Total symptoms were reduced 20.78% (p < 0.0001) by the end of the study. Equally significant was a 37.8% improvement in the relative knee functionality.** 

No adverse events were observed in either study. 

BiovaPlex is eco-smart, “green,” and 100% made in the USA!

Biova® is committed to the production of high quality, all natural products in a sustainable, environmentally sensitive, and all natural manner. 

An underutilized raw material, eggshell, is harvested from USDA inspected and regulated egg breaking facilities for processing. Eggshells and their attached membranes are then separated from each other via our all natural OvaPure patented (U.S. Patent No. 7,584,909), mechanical process. The concentrated membrane is further processed utilizing Biova’s patented (U.S. Patent No. 8,211,477), proprietary Hydro5™ process. This process, developed at our facility within the Iowa State University Research Park, yields low-ash, water soluble egg membrane that is rich in available and measurable nutritional components. BiovaPlex is a resulting ingredient.

Key BiovaPlex Facts

• Canine, equine, feline friendly

• High palatability—friendly taste profile

• Low inclusion rates—easy formulation

• Water soluble for multiple, unique delivery options

• High protein purity—low ash

• Extensive Certificate of Analysis on every lot

• Product consistency and nutrient integrity are maintained from batch to batch

Is BiovaPlex Safe?  YES!

Direct research and a thorough review of published scientific literature yielded no indications
or suggestions of possible concern regarding the safety and tolerability of egg membrane, the origin
of BiovaPlex®.**



  • Visit with Biova at: 


    SupplySide West 

    Las Vegas, NV

    Booth #BB174

    September 26-28, 2017