offers proven elements to support skin care and reduce the visible signs of aging. Applied topically, BiovaDerm® helps:*


• Reduce the appearance of fine lines and wrinkles 

• Hydrate and moisturize skin 

• Improve skin tone and resilience

• Make skin look smoother, firmer, younger at any age 

• Protect skin from free radicals and oxidative damage associated with aging 

• Fight oxidative stress 

• Increase the moisture content of skin 

• Improve skin’s texture and feel

What is BiovaDerm?

Advanced technology allows BiovaDerm® to retain the natural ratios of key elements found in water soluble egg membrane (WSEM), beneficial to skin. These include:

• Collagen—fibrous protein critical to cartilage strength and elasticity 

• Elastin—a protein critical to skin, cardiovascular, cartilage, and spinal column health; Elastin gives tissue the elastic tension and ability to resume its shape after stretching

• Desmosine and Isodesmosine—two little known amino acids responsible for elastin’s elastic or “rubbery” properties

• Glycosaminoglycans (GAGs) including: Glucosamine and Chondroitin—vital polysaccharides which serve as structural components of connective tissue, interstitial fluids, and skeletal structures

Is BiovaDerm® supported by research?  YES!

InVitro studies demonstrated statistically significant inhibition of Reactive Oxygen Species (ROS) formation, Lipoxygenase inhibition. Strong anti-microbial migratory behavior in PMN cells was observed along with response to the inflammatory mediators IL-8 and LTB4, with a particular strong and clear inhibition of LTB4-mediated migration. Apoptotic and necrotic cell death were also reduced under conditions of oxidative stress.**

An open-label study published in Clinical, Cosmetic and Investigational Dermatology (DovePress; 14 October 2016 Volume 2016:9 Pages 357-66) showed daily topical use of BiovaDerm on facial skin significantly reduced the appearance of wrinkles after eight weeks, as measured across three parameters: roughness, contour and depth. This study corroborates results seen in Biova’s prior clinical efficacy trials with 23 subjects conducted over 3 different time periods of 1, 2, and 4 weeks. The net results included treatment effects that ranged from a low of 5% to a high of 60% decrease in wrinkles. These benefits proved long lasting, extending beyond 2 weeks after use was discontinued.**  No adverse events were observed. 

Further, researchers point to WSEM's association with additional mechanisms of cellular activity whereby BiovaDerm might offer natural skin health support and restoration, especially under conditions of oxidative stress, thus contributing to prophylactic anti-aging effects among other applications.  

The most recent research and a video abstract can be found at:

BiovaDerm® is eco-smart, “green,” and 100% made in the USA!

Biova® is committed to the production of high quality, natural ingredients in a sustainable, environmentally sensitive, and all natural manner. 

An underutilized raw material, “eggshell,” is harvested from “egg breaking” facilities for processing. Eggshells and their attached membranes are then separated from each other via our all natural OvaPure patented (U.S. Patent No. 7,584,909), mechanical process. The concentrated membrane is further processed utilizing Biova’s patented (U.S. Patent No. 8,211,477), proprietary Hydro5 process. This process, developed at our facility within the Iowa State University Research Park, yields low-ash, water soluble egg membrane that is rich in available and measurable nutritional components. BiovaDerm® is a resulting ingredient.

BiovaDerm Key Facts

• Water soluble for effective delivery options

• Very mild, easy-to-mask scent

• Product consistency and nutrient integrity in every lot

• An all natural ingredient

• High protein purity

• Extensive Certificate of Analysis on every batch

• Off-white color

BiovaDerm is safe.

Direct research and a thorough review of published scientific literature yielded no indications or suggestions of possible concern regarding the safety and tolerability of egg membrane, the origin of BiovaDerm®.** 

  • Visit with Biova at: 


    SupplySide West 

    Las Vegas, NV

    Booth #BB174

    September 26-28, 2017